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Anti-Peptide YY Antibody
| 产品编号： | 4112062 |
| 规格： | from chicken, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Peptide YY Antibody
Peptide YY1, PYYPYY-I, Peptide tyrosine tyrosine, Peptide YY(3-36), PYY-II, Peptide YY
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Peptide YY (UniProt P10082; also known as Peptide tyrosine tyrosine, PYY, PYY-I) is encoded by the PYY (also known as PYY1) gene (Gene ID 5697) in human. Peptide YY is initially produced as a preproprotein with a signal and a propeptide sequence (aa 1-28 and aa 68-97, respectively). There are two major forms of mature peptide YY corresponding to aa 29-64 and aa 31-64 of the prepro sequence, commonly known as YY(1-36) and YY(3-36), respectively. PYY is one of several well recognized circulating anorexigenic peptides, whose productions increase post-prandially. PYY and glucagon-like peptide 1 (GLP-1) are released from L cells that predominate in the distal ileum and colon. The melanocortin-4 receptor (MC4R) is reported to mediate PYY and GLP-1 release from enteroendocrine L cells upon melanocortin peptides stimulation. |
| Specificity【特异性】 | Reacts with prepro-, pro-, and mature peptide YY & peptide YY(3-36). |
| Immunogen【免疫原】 | Epitope: Mature Peptide YY KLH-conjugated linear peptide corresponding to the mature human peptide YY. |
| Application【应用】 | Anti-Peptide YY Antibody, Cat. No. ABN457, is a highly specific chicken Polyclonal antibody, that targets Peptide YY and has been tested in Western Blotting, Immunohistochemistry. Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Peptide YY in rat colon tissue. |
| Quality【质量】 | Evaluated by Western Blotting in rat small intestine tissue lysate. Western Blotting Analysis: 0.25 µg/mL of this antibody detected Peptide YY in 10 µg of rat small intestine tissue lysate. |
| Other Notes【其他说明】 | Affinity purified |
产品性质
| biological source【生物来源】 | chicken |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | rat, mouse |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgY |
| NCBI accession no.【NCBI登记号】 | NP_004151 |
| UniProt accession no.【UniProt登记号】 | P10082 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~11 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
