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Anti-Phospho-AMPKa1/AMPKa2-T183/T172 antibody produced in rabbit
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | liquid |
species reactivity | human, mouse |
concentration【浓度】 | 3.2 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | Q13131/P54646 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
基本信息
General description【一般描述】 | AMPK belongs to the ser/thr protein kinase family. Alpha subunit is the catalytic subunit of the 5′-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. |
Immunogen【免疫原】 | A phospho synthetic peptide corresponding to residues surrounding T183/T172 of human AMPKa1/AMPKa2. |
Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |