Anti-Phospho-CHEK1-S280 antibody produced in rabbit

rabbit

100

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

43
50
54

human, mouse, rat

1.66 mg/ml

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:200-1:2000

O14757

wet ice

−20℃

human ... CHEK1(1111)

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.

A synthetic phosphorylated peptide around S280 of human CHEK1 (NP_001265.2).

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

12 - Non Combustible Liquids

WGK 1