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Anti-Phospho-MDM2-S166 antibody produced in rabbit
产品别名
Anti-Phospho-MDM2-S166 antibody produced in rabbit
ACTFS
HDMX
MDM2
HDM2
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 11-14 24-55 |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | 0.63 mg/ml |
| technique(s) | immunofluorescence: 1:50-1:100 western blot: 1:500-1:1000 |
| UniProt accession no.【UniProt登记号】 | Q00987 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MDM2(4193) |
基本信息
| General description【一般描述】 | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |
| Immunogen【免疫原】 | A synthetic phosphorylated peptide around S166 of human MDM2 (NP_002383.2). |
| Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
| Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
