您的位置：首页 > 产品中心 > Anti-PRDM16 Antibody
Anti-PRDM16 Antibody
| 产品编号： | 4113098 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PRDM16 Antibody
PR domain containing 16, MEL1, PFM13, KIAA1675, MEL1, MDS1/EVI1-like gene 1, Transcription factor MEL1, PR domain zinc finger protein 16
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | PR domain zinc finger protein 16 (PRDM16) is also called Transcription factor MEL1 (MDS1/EVI1-like gene 1). PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain. PRDM16 is expressed in the uterus and kidney. PRDM16 regulates transcription through DNA binding and plays a role in the differentiation of myoblastic precursors into brown adipose tissue (BAT), and represses TGF-beta signalling. Translocations in PRDM16 occur in subsets of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) cases. |
| Specificity【特异性】 | This antibody can recognize all four isoforms of PRDM16. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human PRDM16. |
| Application【应用】 | Research Sub Category Pluripotent & Early Differentiation Detect PRDM16 using this rabbit polyclonal antibody, Anti-PRDM16 Antibody validated for use in western blotting, IHC & Immunofluorescence. Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PRDM16 in rat brain tissue. Immunofluorescence Analysis: 20 μg/mL from a representative lot detected PRDM16 in human brain cells. Research Category Stem Cell Research |
| Quality【质量】 | Evaluated by Western Blotting in rat brain tissue lysate. Western Blotting Analysis: 2 µg/mL of this antibody detected PRDM16 in 15 µg of rat brain tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Rat brain tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | rat, human |
| technique(s) | immunofluorescence: suitable immunohistochemistry: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9HAZ2 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~100 kDa, ~135 kDa and ~150 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 4 isoforms between ~120 kDa and ~140 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
