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Anti-RIG-1 antibody produced in rabbit

产品编号:4113702
规格:purified antibody (DEAE)
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4113702100 μG4800
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified antibody (DEAE)
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
liquid
species reactivity
mouse, human, rat
concentration【浓度】
1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype【同位素/亚型】
IgG
UniProt accession no.【UniProt登记号】
O95786
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... DDX58(23586)
基本信息
General description【一般描述】
RIG-1 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKKε through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus.
Immunogen【免疫原】
RIG-1 antibody was raised against human GST-tagged RIG-1 protein.
Application【应用】
RIG-1 antibody can be used for the detection of RIG-1 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human and rat samples. All other applications and species not yet tested.
Physical form【外形】
Supplied in PBS containing 0.02% sodium azide.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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