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Anti-RIPK2 Antibody, clone 1H10.1
产品别名
Anti-RIPK2 Antibody, clone 1H10.1
Receptor-interacting serine/threonine-protein kinase 2, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP-like-interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, Tyrosine-prote
基本信息
| eCl@ss | 32160702 |
| General description【一般描述】 | Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1; EC 2.7.10.2; UniProt O43353; also known as Receptor-interacting protein 2, CARD-carrying kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, Growth-inhibiting gene 30, Receptor-interacting protein-like interacting caspase-like apoptosis regulatory protein kinase, RIP-2, RIP-like interacting CLARP kinase, Tyrosine-protein kinase RIPK2) is encoded by the RIPK2 (also known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2) gene (Gene ID 8767) in human. RIPK2 is a dual-specificity kinase that exhibits both serine/threonine as well as tyrosine kinase activities. RIPK2 participates in transducing cellular inflammatory response by propagating signaling downstream of the intracellular peptidoglycan sensors NOD1 and NOD2. |
| Specificity【特异性】 | Expected to react with both isoforms. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human RIPK2. |
| Application【应用】 | Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected RIPK2 in human prostate and human placenta tissue. Research Sub Category Apoptosis - Additional Research Category Apoptosis & Cancer Anti-RIPK2 Antibody, clone 1H10.1 is an antibody against RIPK2 for use in Western Blotting and Immunohistochemistry. |
| Quality【质量】 | Evaluated by Western Blotting in human placenta tissue lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected RIPK2 in 10 µg of human placenta tissue lysate. |
| Physical form【外形】 | Purified by Ion-Exchange Chromatography Purified mouse monoclonal IgMκ antibody in PBS with 0.05% sodium azide. Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 1H10.1, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgMκ |
| NCBI accession no.【NCBI登记号】 | NP_003812 |
| UniProt accession no.【UniProt登记号】 | O43353 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... RIPK2(8767) |
产品说明
| Target description【目标描述】 | ~60 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
