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Anti-RRM2 Antibody, clone 4D1.2
产品别名
Anti-RRM2 Antibody, clone 4D1.2
Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Ribonucleoside-diphosphate reductase subunit M2 (RRM2) is a cytoplasmic protein, which catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates, and plays an important role in DNA damage and repair. RRM2 has been implicated in various types of cancer. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human RRM2. |
| Application【应用】 | Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected RRM2 in HepG2 and A431 cells. Research Sub Category Apoptosis - Additional Detect Ribonucleotide Reductase using this mouse monoclonal antibody, Anti-RRM2 Antibody, clone 4D1.2 validated for use in western blotting & ICC. Research Category Apoptosis & Cancer |
| Quality【质量】 | Evaluated by Western Blotting in HeLa cell lysate. Western Blotting Analysis: 0.2 µg/mL of this antibody detected RRM2 in 10 µg of HeLa cell lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control HeLa cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 4D1.2, monoclonal |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001025 |
| UniProt accession no.【UniProt登记号】 | P31350 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... RRM2(6241) |
产品说明
| Target description【目标描述】 | ~45 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
