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Anti-RSK4 Antibody
产品编号: | 4113870 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-RSK4 Antibody
Q9UK32, KS6A6_HUMAN, RPS6KA6, RSK4, Q9UK32, B2R854, Q6FHX2, Q8WX28, Q9H4S6, Ribosomal protein S6 kinase alpha-6, p90RSK6
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | RSK1, RSK2, RSK3, and RSK4 (ribosomal protein S6 kinase, 90 kDa, polypeptide 1,2,3, and 4; S6K-alpha 1,2,3, and 4) are Ser/Thr kinases which are activated by MAP Kinases. Ribosomal S6-kinase 4 (RSK4) is thought to be mapped in the critical region that is commonly deleted in X-linked deafness type 3, mental retardation, and choroideremia. It may be involved in normal neuronal development. RSK4 is also thought to play a role in non-growth factor signaling and may also be important in tumor suppression. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the C-terminus of Human RSK4. Epitope: C-terminus |
Application【应用】 | Research Sub Category Kinases & Phosphatases General Post-translation Modification Research Category Signaling This Anti-RSK4 Antibody is validated for use in Western Blotting and Immunoprecipitation for the detection of RSK4. Immunoprecipitation analysis: 10 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.5 mg PC12 or EGF treated PC12 cell lysate Immunoprecipitation analysis: 5 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.665mg of PC12 cell lysate. Uncharacterized bands may be detected at high antibody concentration or longer exposures |
Quality【质量】 | Evaluated by Western Blotting in rat PC12 cell lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected RSK4 in 10 µg of rat PC12 cell lysate. |
Linkage【联系】 | Replaces: 04-1132 |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Antigen Affinity Purified |
Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | rat |
species reactivity (predicted by homology) | bovine (based on 100% sequence homology), human (based on 100% sequence homology) |
technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_055311 |
UniProt accession no.【UniProt登记号】 | Q9UK32 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~83 kDa observed. Uncharacterized band(s) may appear in some lysates. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |