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Anti-SERCA2 Antibody, clone IID8
产品别名
Anti-SERCA2 Antibody, clone IID8
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SR Ca(2+)-ATPase 2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic r
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | The sarcoplasmic reticulum of striated muscle is a specialized intracellular membrane system that plays a critical role in the contraction and relaxation of muscle. The sarco/endoplasmic reticulum Ca2+ ATPases (SERCAs) mediate Ca2+ uptake into intracellular stores. SERCA mediated Ca2+ uptake induces and maintains muscular relaxation. SERCA1 is expressed in fast-twitch muscles, whereas SERCA2 is expressed in cardiac and slow-twitch muscles. SERCA2 plays an important part in regulating cardiac contractile function. |
Specificity【特异性】 | The antibody recognizes SERCA2. |
Immunogen【免疫原】 | Purified canine cardiac sarcoplasmic reticulum. Epitope: Unknown |
Application【应用】 | Research Category Cell Structure Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Eizema, 2007). Research Sub Category Cytoskeleton Cytoskeletal Signaling Anti-SERCA2 Antibody, clone IID8 is an antibody against SERCA2 for use in WB, IC, IH. |
Quality【质量】 | Evaluated by Western Blot in HEK293 cell lysate. Western Blot Analysis: 0.5 µg/ml of the antibody detected SERCA2 in 10 µg of HEK293 cell lysate. |
Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. Format: Purified Protein G Purified |
Analysis Note【分析说明】 | Control HEK293 cell lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | IID8, monoclonal |
species reactivity | human |
technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_001003214 |
UniProt accession no.【UniProt登记号】 | O46674 |
shipped in【运输】 | wet ice |
Gene Information | human ... ATP2A2(488) |
产品说明
Target description【目标描述】 | ~ 110 kDa |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |