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Anti-Serpinf2 Antibody
| 产品编号： | 4114170 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Serpinf2 Antibody
Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Serpin F2, also known as Alpha-2-antiplasmin Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, and encoded by the gene name SERPINF2, AAP, or PLI, is a member of the Serpin family. Serpin F2 is a serine protease inhibitor. As an inhibitor, the major targets of Serpin F2 are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. Serpin F2 forms protease inhibiting heterodimer with TMPRSS7. Serpin F2 is expressed by the liver and secreted in plasma. Mutations in Serpin F2 have been associated with Alpha-2-plasmin inhibitor deficiency (APLID), an autosomal recessive disorder resulting in severe hemorrhagic diathesis. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the Alpha-2-antiplasmin mature chain of human Serpinf2. Epitope: Alpha-2-antiplasmin mature chain |
| Application【应用】 | This Anti-Serpinf2 antibody is validated for use in WB, IH for the detection of Serpinf2. Research Category Signaling Research Sub Category Signaling Neuroscience Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Serpinf2 in human liver and human liver cancer tissue. |
| Quality【质量】 | Evaluated by Western Blotting in human liver tissue lysate. Western Blotting Analysis: 2.0 µg/mL of this antibody detected Serpinf2 in 10 µg of human liver tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| species reactivity (predicted by homology) | primate (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_000925 |
| UniProt accession no.【UniProt登记号】 | P08697 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~73 kDa observed. Predicated to work with both glycos and non-glycos isoforms. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
