Anti-SLC6A4/5HTT/SERT antibody produced in goat

MFCD01634174

NA.41

Solute carrier family 6 member 4 (SLC6A4), also known as 5-hydroxytryptamine transporter (5-HTT), is an integral membrane protein, encoded by the gene mapped to human chromosome 17q11.2. The encoded protein is a member of SLC6 gene family and is mainly expressed in brain and blood cells.

Peptide with sequence C-LHQGERETWGK from the internal region of the protein sequence according to NP_001036.1.

Anti-SLC6A4/5HTT/SERT antibody produced in goat has been used in immunolabelling and Western blotting.

Solute carrier family 6 member 4 (SLC6A4) catalyzes the transport of neurotransmitter serotonin from the synaptic space into presynaptic neurons. It also plays a vital role in mood and anxiety regulation. Mutation on the gene might alter the expression of serotonin (5HT) in the synaptic cleft, which ultimately leads to schizophrenia. Allelic variations in the gene increase the risk of susceptibility to autism and rigid-compulsive behaviors.

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Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

100

goat

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human

indirect ELISA: suitable
western blot: suitable

P31645

dry ice

−20℃

human ... SLC6A4(6532)

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GHS07

Warning

H315 - H319

P305 + P351 + P338

Eye Irrit. 2 - Skin Irrit. 2

12 - Non Combustible Liquids

WGK 2