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Anti-SRp55 Antibody, clone 9-1-56
产品别名
Anti-SRp55 Antibody, clone 9-1-56
splicing factor, arginine/serine-rich 6, arginine/serine-rich splicing factor 6, splicing factor, arginine/serine-rich, 55 kDa, Pre-mRNA-splicing factor SRP55, pre-mRNA splicing factor SRP55
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Pre-mRNA-splicing factor SRp55 is a member of the serine/arginine-rich (SR) protein family. This group of proteins is found mainly in the nucleus where they play a critical role in regulated and constitutive splicing of precursor mRNAs. SRp55 is involved in the constitutive process for mRNA splicing, and is able to mediate alternative splice site selection. Considered one of the more ubiquitous of the splice factors, SRp55 is upregulated in response to DNA damage when p53 is lacking. SRp55 is significantly phosphorylated on RS domain serine residues. |
| Immunogen【免疫原】 | Epitope: Not determined MBP-tagged recombinant protein corresponding to human SRp55. |
| Application【应用】 | Research Category Epigenetics & Nuclear Function Research Sub Category RNA Metabolism & Binding Proteins Use Anti-SRp55 Antibody, clone 9-1-56 (Mouse Monoclonal Antibody) validated in WB, IP, ICC, IHC to detect SRp55 also known as arginine/serine-rich splicing factor 6, Pre-mRNA-splicing factor SRP55. |
| Quality【质量】 | Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected SRp55 on 10 µg of HeLa cell lysate. |
| Physical form【外形】 | Format: Purified Protein G Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl without 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control HeLa cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 9-1-56, monoclonal |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_006266 |
| UniProt accession no.【UniProt登记号】 | Q13247 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~ 43 kDa observed. 40 kDa calculated. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
