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Anti-TCIM (N-terminal) antibody produced in rabbit
产品别名
Anti-TCIM (N-terminal) antibody produced in rabbit
C8orf4
TC-1
TC1
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 12 kDa |
| species reactivity (predicted by homology) | rat, guinea pig, horse, canine, rabbit, human, mouse, bovine |
| concentration【浓度】 | 0.5 mg/mL |
| technique(s) | western blot: 1 μg/mL |
| NCBI accession no.【NCBI登记号】 | NM_020130 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TCIM(57396) |
基本信息
| General description【一般描述】 | This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N-terminal region of Human C8orf4 |
| Sequence【序列】 | Synthetic peptide located within the following region: TASRKKAVGNIFENTDQESLERLFRNSGDKKAEERAKIIFAIDQDVEEKT |
| Physical form【外形】 | Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | nwg |
