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Anti-TGFBR3, clone 1C5H11 Antibody
| 产品编号： | 4115166 |
| 规格： | ascites fluid, clone 1C5H11, from mouse |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-TGFBR3, clone 1C5H11 Antibody
Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III, TGFBR3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3 or TGFR-3), also known as Betaglycan or Transforming growth factor beta receptor III (TGF-beta receptor type III), and encoded by the gene name TGFBR3, is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is extensively modified by glycosaminoglycan groups (GAG). |
| Immunogen【免疫原】 | Purified recombinant fragment of human TGFBR3 expressed in E. Coli |
| Application【应用】 | Flow Cytometry Analysis: A 1:200-1:400 dilution from a representative lot detected TGFBR3 in MOLT4 cells. ELISA: A representative lot was used on Control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct). Anti-TGFBR3, clone 1C5H11 Antibody is an antibody against TGFBR3 for use in western blotting, flow cytometry & ELISA. Research Sub Category Tumor Markers Research Category Apoptosis & Cancer |
| Quality【质量】 | Evaluated by Western Blotting in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates. Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected TGFBR3 in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates. |
| Physical form【外形】 | Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide. Unpurified |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 1C5H11, monoclonal |
| species reactivity | human, mouse |
| technique(s) | ELISA: suitable flow cytometry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2b |
| UniProt accession no.【UniProt登记号】 | Q03167 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... TGFBR3(7049) |
产品说明
| Target description【目标描述】 | ~93 kDa observed. Uncharacterized bands may be observed in some lysate(s). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
