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Anti-THAP11 (Ronin) Antibody
| 产品编号： | 4115182 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-THAP11 (Ronin) Antibody
THAP domain-containing protein 11
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | THAP11 (Ronin) is a transcriptional repressor which is predominantly expressed in embryonic stem (ES) cells. It contains a THAP-type zinc finger domain which is characteristic of the THAP 11 family members. In ES cells, THAP11 interacts with the transcriptional co-regulator HCF-1, to recruit chromatin-modifying proteins such as members of the polycomb family of proteins, to induce gene repression. THAP11 targets genes involved in metabolism, transcriptional initiation, and messenger RNA splicing. It plays an important role in maintaining the pluripotent state of ES cells. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human THAP11. |
| Application【应用】 | Research Sub Category Apoptosis - Additional This Anti-THAP11 (Ronin) Antibody is validated for use in Western Blotting, IHC for the detection of THAP11 (Ronin). Research Category Apoptosis & Cancer Western Blot Analysis: 1 µg/mL from a representative lot detected THAP11 on 10 µg of mouse liver tissue lysate. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected THAP11 in mouse cardiac muscle and mouse liver tissues. |
| Quality【质量】 | Evaluated by Western Blot in mouse heart tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected THAP11 on 10 µg of mouse heart tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Mouse heart tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse |
| species reactivity (predicted by homology) | human (immunogen homology), rat (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_065190 |
| UniProt accession no.【UniProt登记号】 | Q96EK4 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... THAP11(57215) |
产品说明
| Target description【目标描述】 | ~48 kDa observed. Uncharacterized bands appear at ~20-25 kDa in some lysates. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
