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Anti-YB-1/YBX1 antibody produced in rabbit

产品编号:4116159
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
41161594660
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody product type
primary antibodies
clone【克隆】
monoclonal
form【形式】
liquid
concentration【浓度】
0.4 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
UniProt accession no.【UniProt登记号】
P67809
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... YBX1(4904)
基本信息
General description【一般描述】
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
Immunogen【免疫原】
A synthesized peptide derived from human YB-1/YBX1
Physical form【外形】
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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