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BioTracker 640 Red C2(FM4-64) Synaptic Dye
产品编号: | 4116826 |
规格: | Live cell imaging synaptic dye that detects neural synaptic activitiy at neuromuscular junctions and synapses. |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
BioTracker 640 Red C2(FM4-64) Synaptic Dye
Live cell imaging probe
产品性质
technique(s) | cell based assay: suitable |
Detection Method | fluorometric |
shipped in【运输】 | ambient |
基本信息
General description【一般描述】 | BioTracker synaptic dyes are a series of fluorescent cationic styryl dyes developed to follow synaptic activities at neuromuscular junctions or synapses. These dyes typically have a lipophilic tail at one end and a highly hydrophilic at the other end. In the presence of cells or tissue preparations, the dyes partition between the aqueous phase, where the dyes are virtually non-fluorescent, and the outer leaflet of the cell surface membranes, where the dyes insert the lipophilic end into the membranes and become intensely fluorescent. During endocytosis following nerve stimulation, the dyes become trapped inside the vesicles. Thus, after washing off the dyes on the cell surface, the fluorescent signal is proportional to the number of newly formed vesicles. On the other hand, during exocytosis, the dyes are released from the vesicles along with neurotransmitters, causing a decrease in fluorescent signal. As a result, the change in fluorescent intensity reflects the amount of endocytosis/exocytosis or synaptic activity. Spectral Properties Absorbance (Membranes): 510 nm Emission (Membranes): 750 nm |
Application【应用】 | Research Sub Category Live Cell Dye Research Category Cell Imaging Live cell fluorescent imaging Live cell imaging synaptic dye that detects neural synaptic activitiy at neuromuscular junctions and synapses. |
Quality【质量】 | Spectral Properties Absorbance (Membranes): 510 nm Emission (Membranes): 750 nm |
Physical form【外形】 | Lyophilized |
产品说明
Storage and Stability【储存及稳定性】 | Store BioTracker 640 Red C2(FM4-64) Synaptic Dye at 2-8°C, protected from light. Stock solutions can be prepared at 10 mM and stored at 4°C or -20°C for six months or longer. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |