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FABP3 human
产品编号: | 4118598 |
规格: | recombinant, expressed in E. coli, ≥98% (SDS-PAGE) |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
FABP3 human
Fatty acid-binding protein heart
Heart-type fatty acid-binding protein
M-FABP
Mammary-derived growth inhibitor
H-FABP
Muscle fatty acid-binding protein
基本信息
MDL number | MFCD00285932 |
NACRES | NA.32 |
General description【一般描述】 | Fatty acid binding proteins (FABPs) are intracellular proteins with a low molecular weight. They exhibit high affinity for small lipophilic ligands. FABP-3 is expressed in the skeletal muscle, heart, brain and brown adipose tissue. The gene encoding it is localized on human chromosome 1p35. |
Biochem/physiol Actions【生化/生理作用】 | Studies suggest that fatty acid binding protein (FABPs) are involved in the uptake and metabolism of fatty acids, maintenance of cellular membrane fatty acids levels, intracellular trafficking, modulation of specific enzymes of lipid metabolic pathways, as well as in the modulation of cell growth and differentiation. FABPs have been associated with diabetes, obesity, atherosclerosis and brain function. FABP-3 has a role in glucose and lipid metabolism. It also modulates polysaturated fatty acid uptake and metabolism in neurons. The protein has been associated with schizophrenia, Down′s syndrome, Alzheimer′s disease and autism spectrum disorder. |
Physical form【外形】 | Sterile filtered and Lyophilized without additives. |
Reconstitution【重悬】 | Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
产品性质
biological source【生物来源】 | human |
recombinant【重组】 | expressed in E. coli |
Assay【测定】 | ≥98% (SDS-PAGE) |
form【形式】 | lyophilized |
mol wt【分子量】 | ~19 kDa |
packaging【包装】 | pkg of 100 μg |
storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
impurities【杂质】 | endotoxin, tested |
NCBI accession no.【NCBI登记号】 | P05413 |
UniProt accession no.【UniProt登记号】 | P05413 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... FABP3(2170) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |