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FGFR4/CD334 human
产品编号: | 4118683 |
规格: | recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE) |
包装规格: | 20 μG,100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
FGFR4/CD334 human
Fibroblast growth factor receptor 4
MGC20292
FGFR-4
JTK2
TKF
基本信息
NACRES | NA.32 |
General description【一般描述】 | Fibroblast growth factor receptor 4(FGFR4) is also known as CD334, JTK2, hydroxyaryl-protein kinase, TKF, protein-tyrosine kinase. The FGFR4 gene provides instructions for making a protein called fibroblast growth factor receptor 4. This protein is part of a family of fibroblast growth factor receptors that share similar structures and functions. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development. The FGFR4 protein interacts with specific growth factors to conduct signals from the environment outside the cell to the nucleus. The nucleus responds to these signals by switching on or off appropriate genes that help the cell adjust to changes in the environment. In response, the cell might divide, move, or mature to take on specialized functions. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. The FGFR4 gene may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye. |
Physical form【外形】 | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃. |
产品性质
biological source【生物来源】 | human |
recombinant【重组】 | expressed in HEK 293 cells |
tag【标签】 | 6-His tagged (C-terminus) |
Assay【测定】 | ≥98% (SDS-PAGE) |
form【形式】 | lyophilized |
mol wt【分子量】 | calculated mol wt 40 kDa observed mol wt 60 kDa by SDS-PAGE (DTT-reduced. Leu 22 is the predicted N-terminal.) |
packaging【包装】 | pkg of 20 and 100 μg |
UniProt accession no.【UniProt登记号】 | P22455 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... FGFR4(2264) |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |