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Fingolimod hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4118691 | 500 mg | 12710 |
产品别名
162359-56-0
Fingolimod hydrochloride
2-Amino-2-[2-(4-octyl-phenyl)-ethyl]-propane-1,3-diol hydrochloride
FTY720
2-氨基-2- [2-(4-辛基-苯基)-乙基]-丙烷-1,3-二醇 盐酸盐
芬戈莫德 盐酸盐
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H33NO2 · HCl |
| Molecular weight | 343.93 |
| General description【一般描述】 | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| Biochem/physiol Actions【生化/生理作用】 | FTY720是一种免疫调节药物以及1-磷酸鞘氨醇(S1P)受体的调节剂。 鞘氨醇激酶对FTY270的磷酸化可导致S1P1R的内化，从而螯合淋巴结中的淋巴细胞，阻止它们参与自身免疫反应。 临床上，它已被批准用于治疗多发性硬化症(MS)。研究显示其可通过抑制S1PR阻断和逆转紫杉醇诱导的化疗诱导的周围神经病变(CIPN)，并可抑制小鼠脑海马中组蛋白脱乙酰酶的活性，从而调节记忆。 |
| Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAC6340 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
| grade【等级】 | certified reference material pharmaceutical secondary standard |
| description【描述】 | Pharmaceutical Secondary Standard; Certified Reference Material |
| form【形式】 | powder |
| packaging【包装】 | pkg of 500 mg |
| pharmacopeia traceability【药典可追溯性】 | traceable to PhEur Y0002055 traceable to USP 1270480 |
| storage temp.【储存温度】 | 2-30℃ |
| InChI | 1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H |
| InChI key | SWZTYAVBMYWFGS-UHFFFAOYSA-N |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H373 |
| Precautionary Statements | P260 - P314 - P501 |
| Hazard Classifications【危险分类】 | STOT RE 2 |
| Target Organs【靶器官】 | Immune system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
