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Fingolimod hydrochloride
| 产品编号： | 4118692 |
| 规格： | United States Pharmacopeia (USP) Reference Standard |
| CAS NO： | 162359-56-0 |
| 包装规格： | 300 MG |
| 产品类别： | 进口试剂 |
| 品牌： | USP |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4118692 | 300 MG | 29020 |
产品别名
162359-56-0
Fingolimod hydrochloride
2-Amino-2-[2-(4-octyl-phenyl)-ethyl]-propane-1,3-diol hydrochloride
FTY720
2-氨基-2- [2-(4-辛基-苯基)-乙基]-丙烷-1,3-二醇 盐酸盐
芬戈莫德 盐酸盐
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H33NO2 · HCl |
| Molecular weight | 343.93 |
| General description【一般描述】 | Fingolimod Hydrochloride (fingolimod HCl), an S1P-receptor modulator, belongs to the class of synthetic glucocorticoid steroid drugs. This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. |
| Application【应用】 | Fingolimod Hydrochloride USP reference standard may be used to quantify the analyte in gel, capsule and other pharmaceutical formulations, active pharmaceutical ingredient (API) and pharmaceutical dosage forms by liquid chromatography (LC) based techniques. |
| Biochem/physiol Actions【生化/生理作用】 | FTY720是一种免疫调节药物以及1-磷酸鞘氨醇(S1P)受体的调节剂。 鞘氨醇激酶对FTY270的磷酸化可导致S1P1R的内化，从而螯合淋巴结中的淋巴细胞，阻止它们参与自身免疫反应。 临床上，它已被批准用于治疗多发性硬化症(MS)。研究显示其可通过抑制S1PR阻断和逆转紫杉醇诱导的化疗诱导的周围神经病变(CIPN)，并可抑制小鼠脑海马中组蛋白脱乙酰酶的活性，从而调节记忆。 |
| Analysis Note【分析说明】 | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Other Notes【其他说明】 | Sales restrictions may apply. |
产品性质
| biological source【生物来源】 | synthetic |
| agency | USP |
| form【形式】 | powder |
| manufacturer/tradename | USP |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: soluble ethyl acetate: soluble water: soluble |
| application(s) | pharmaceutical |
| storage temp.【储存温度】 | 2-8℃ |
| InChI | 1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H |
| InChI key | SWZTYAVBMYWFGS-UHFFFAOYSA-N |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H373 |
| Precautionary Statements | P260 - P314 - P501 |
| Hazard Classifications【危险分类】 | STOT RE 2 |
| Target Organs【靶器官】 | Immune system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
