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Fmoc-N-amido-dPEG®8-acid
产品别名
Fmoc-N-amido-dPEG®8-acid
Fmoc-NH-PEG8-acid
Fmoc-N-amido-PEG8-acid
Fmoc-N-amido-PEG8-COOH
Fmoc-PEG-acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C34H49NO12 |
| Molecular weight | 663.75 |
| MDL number | MFCD11041143 |
| Features and Benefits【特点和优势】 | Fmoc-N-amido-dPEG8-acid is a monodisperse PEG product that is useful for peptide synthesis. The 28-atom dPEG spacer allows the introduction of a medium-length, hydrophilic spacer onto either end of a peptide chain or between two peptide chains. The flexible dPEG spacer conjugates to peptides using conventional peptide synthesis chemistry. Peptide PEGylation imparts water solubility to hydrophobic peptide chains. Also, PEGylated peptides have expanded hydrodynamic volumes, which can reduce or eliminate renal clearance, and are protected from proteolysis. The combination of decreased renal clearance and protection from proteolysis contributes to longer in vivo circulation times for PEGylated (as compared to non-PEGylated) peptides. Additionally, PEGylation diminishes a peptide′s antigenicity. This product is part of the Fmoc-N-amido-dPEGn-acid (n=2, 3, 4, 5, 6, 8, 12, 24, 36) product series. |
| Legal Information【法律信息】 | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 dPEG is a registered trademark of Quanta BioDesign |
产品性质
| Assay【测定】 | >95% (HPLC) |
| form【形式】 | solid or viscous liquid |
| reaction suitability | reaction type: Pegylations |
| polymer architecture【聚合物结构设计】 | shape: linear functionality: heterobifunctional |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
