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Fn14 (human): FC (human)
| 产品编号： | 4118782 |
| 规格： | recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Fn14 (human): FC (human)
E1A-associated protein p300
CD266
Tumor necrosis factor receptor superfamily member 12A
FGF-inducible 14
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke. |
| Physical form【外形】 | Lyophilized from PBS. |
| Reconstitution【重悬】 | Reconstitute with 50 μL deionized water. |
| Other Notes【其他说明】 | The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in HEK 293 cells |
| Assay【测定】 | >95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~35 kDa by SDS-PAGE |
| packaging【包装】 | pkg of 50 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | <0.1 EU/μg endotoxin, tested |
| color【颜色】 | white |
| UniProt accession no.【UniProt登记号】 | Q9NP84 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... TNFRSF12A(51330) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
