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FRS3, GST tagged human

产品编号:4118814
规格:recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
411881450 μG4340
产品别名

FRS3, GST tagged human

SNT2

FRS2B

FRS2β

MGC17167

基本信息
NACRES
NA.32
General description【一般描述】
FRS3 or fibroblast growth factor receptor substrate 3 is a peripheral plasma membrane protein that is a substrate for the fibroblast growth factor receptor. During FGF or NGF stimulation, FRS3 becomes tyrosine phosphorylated and then serves as a platform for the recruitment of multiple signaling proteins for activation of the Ras-MAP kinase signaling cascade. FRS3 is mainly expressed in fibroblast and myoblast cell lines and undergo robust tyrosine phosphorylation in response to several mitogenic ligands. Through interaction with Rho family of small GTPases, FRS3 has been implicated in the reorganization of the actin cytoskeleton and subsequent morphological changes in various cells.
Physical form【外形】
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note【制备说明】
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
产品性质
recombinant【重组】
expressed in baculovirus infected Sf9 cells
Assay【测定】
≥70% (SDS-PAGE)
form【形式】
buffered aqueous glycerol solution
mol wt【分子量】
~87 kDa
NCBI accession no.【NCBI登记号】
NM_006653
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... FRS3(10817)
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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