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Glucose-6-Phosphate Dehydrogenase Assay Kit
产品性质
| Quality Level【质量水平】 | 100 |
| Detection Method | colorimetric |
| relevant disease(s)【相关疾病】 | hematological disorder, anemia |
| storage temp.【储存温度】 | −20℃ |
| suitability【适用性】 | The kit is suitable for the quantitative determination of Glucose-6-Phosphate concentration and evaluation of drug effects on its metabolism in plasma, serum, tissue and culture media, etc. |
基本信息
| General description【一般描述】 | Glucose-6-Phosphate Dehydrogenase (G6PDH) is a cytosolic enzyme in the pentose phosphate pathway which supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PDH reduces nicotinamide adenine dinucleotide phosphate (NADP) to NADPH while oxidizing glucose-6-phosphate (G6P). Humans with a genetic deficiency of G6PDH are predisposed to non-immune hemolytic anemia. |
| Features and Benefits【特点和优势】 |
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| Principle【原理】 | The non-radioactive, colorimetric Glucose-6-Phosphate Dehydrogenase Assay Kit is based on the reduction of tetrazolium salt MTT in a NADPH-coupled enzymatic reaction to a reduced form of MTT which exhibits an absorption maximum at A565 nm. The increase in absorbance at A565 nm is proportional to the enzyme activity. |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H341 |
| Precautionary Statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Classifications【危险分类】 | Muta. 2 |
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 3 |
