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GPX1 human
| 产品编号： | 4119047 |
| 规格： | recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE) |
| CAS NO： | 1451392-36-1 |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
1451392-36-1
GPX1 human
Death receptor 6
Cellular glutathione peroxidase
Glutathione peroxidase 1
GSHPx-1
细胞谷胱甘肽过氧化物酶
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | GPX1 (glutathione peroxidase 1) is a selenoprotein and the gene is mapped to human chromosome 3p21.3. It is present in the cytoplasm and is widely expressed. |
| Biochem/physiol Actions【生化/生理作用】 | GPX1 (glutathione peroxidase 1) is responsible for scavenging free radicals and derivatives. GPXs reduces lipid hydroperoxides to the corresponding alcohols as well as free hydrogen peroxide to water. Mutations in the GPX1 gene are associated with nonalcoholic fatty liver disease (NAFLD) susceptibility. Mutation in GPX1 at C594T is linked with oxidative stress-associated disorders, including prostate cancer and bladder cancer. |
| Physical form【外形】 | Lyophilized from 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl, 1 mM DTT. |
| Reconstitution【重悬】 | Reconstitute with 100 μL deionized water. |
| Other Notes【其他说明】 | Human GPX1 (aa 1-201) is fused at the C-terminus to a His-tag. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| tag【标签】 | His tagged |
| Assay【测定】 | >90% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~25 kDa by SDS-PAGE |
| packaging【包装】 | pkg of 10 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| impurities【杂质】 | <1 EU/μg endotoxin, tested |
| color【颜色】 | white |
| UniProt accession no.【UniProt登记号】 | P07203 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GPX1(2876) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
