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HAVCR1/KIM1/TIM1 human
| 产品编号： | 4119124 |
| 规格： | recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
HAVCR1/KIM1/TIM1 human
TIMD-1
HAVCR-1
TIMD1
hepatitis A virus cellular receptor 1
HAVCR
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in HEK 293 cells |
| tag【标签】 | 6-His tagged (C-terminus) |
| Assay【测定】 | ≥90% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | calculated mol wt 31.3 kDa observed mol wt 80-100 kDa by SDS-PAGE (reducing) (DTT-reduced.) |
| packaging【包装】 | pkg of 10 and 50 μg |
| impurities【杂质】 | <1 EU/μg endotoxin (LAL test) |
| UniProt accession no.【UniProt登记号】 | Q96D42 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HAVCR1(26762) |
基本信息
| General description【一般描述】 | Hepatitis A virus cellular receptor 1 also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. |
| Physical form【外形】 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
| Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃. |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
