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Jagged-2 (human): FC (human)
| 产品编号： | 4119603 |
| 规格： | recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Jagged-2 (human): FC (human)
Protein jagged-2
Alpha-ketoglutarate-dependent dioxygenase FTO
hJ2
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development. |
| Sequence【序列】 | Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG. |
| Physical form【外形】 | Lyophilized. Contains PBS + 0.02 % CHAPS. |
| Reconstitution【重悬】 | Reconstitute with 100μl sterile water. |
产品性质
| recombinant【重组】 | expressed in HEK 293 cells |
| Assay【测定】 | ≥90% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~150 kDa by SDS-PAGE |
| impurities【杂质】 | <0.1 EU/μgtested |
| UniProt accession no.【UniProt登记号】 | Q9Y219 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... JAG2(3714) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
