您的位置：首页 > 产品中心 > m-dPEG®37-NHS ester
m-dPEG®37-NHS ester
产品别名
m-dPEG®37-NHS ester
mPEG1500-NHS ester
m-PEG37-NHS ester
mPEG37-NHS ester
mPEG-NHS ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C80H155NO41 |
| Molecular weight | 1787.07 |
| MDL number | MFCD21363217 |
| Features and Benefits【特点和优势】 | m-dPEG37-NHS ester is a methyl-terminated, single molecular weight, discrete chain length polyethylene glycol (dPEG) spacer. The carboxylic acid moiety on the end of the molecule opposite the methyl cap is activated with N-hydroxysuccinimide (NHS) for facile reaction with free amines. The dPEG spacer is 112 atoms (133.9 Å) long, a monodisperse equivalent of a polymeric PEG1500. m-dPEG37-NHS ester can be used to modify silica shelled quantum dots to make them water-soluble. Also, it has been employed to improve the pharmacokinetic (PK) and biodistribution (BD) properties of an antibody. Carbon nanotubes and inorganic nanoparticles with amine-functionalized surfaces could also be modified to passivate the surface and make it hydrophilic. Overall, proteins and other biomolecules conjugated to this product will have higher water solubility, reduced or eliminated antigenicity, and improved PK and BD properties. |
| Legal Information【法律信息】 | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 dPEG is a registered trademark of Quanta BioDesign |
产品性质
| Assay【测定】 | >95% (HPLC) |
| form【形式】 | solid or viscous liquid |
| reaction suitability | reaction type: Pegylations |
| polymer architecture【聚合物结构设计】 | shape: linear functionality: monofunctional |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
