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MAL-dPEG®8-TFP ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C32H44F4N2O13 |
| Molecular weight | 740.69 |
| MDL number | MFCD28505514 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823941 |
| NACRES | NA.22 |
| Features and Benefits【特点和优势】 | MAL-dPEG®8-TFP ester is a heterobifunctional, linear crosslinking reagent containing a maleimide group on one end of the single molecular weight dPEG® spacer arm and an amine-reactive active ester on the other end. The maleimide group reacts readily and specifically with free sulfhydryl groups in aqueous media at pH 6.5-7.5. The 2,3,5,6-tetrafluorophenyl (TFP) ester is used widely in reactions with primary amines. The TFP-amine reactions can be carried out in aqueous or organic solvent. The dPEG® spacer is hydrophilic and non-immunogenic. Because it is a single molecular weight product, it gives the user precise spatial control. The dPEG® spacer also improves water solubility, decreases immunogenicity, and increases the hydrodynamic volume of the conjugate. The increased hydrodynamic volume results in longer serum half-life in vivo. |
| Legal Information【法律信息】 | Products Protected under U.S. Patents # 7,888,536 B2 dPEG is a registered trademark of Quanta BioDesign |
产品性质
| Assay【测定】 | >90% |
| form【形式】 | solid or viscous liquid |
| reaction suitability | reagent type: cross-linking reagent reactivity: amine reactive reagent type: cross-linking reagent reactivity: thiol reactive |
| polymer architecture【聚合物结构设计】 | shape: linear functionality: heterobifunctional |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C(OC1=C(F)C(F)=CC(F)=C1F)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
