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产品性质
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| Assay【测定】 | 70-95% (SDS-PAGE) |
| form【形式】 | frozen liquid |
| mol wt【分子量】 | ~82 kDa |
| concentration【浓度】 | 0.1 μg/μL |
| accession no.【登记号】 | NM_004567 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PFKFB4(5210) |
基本信息
| Application【应用】 | Useful for Western blot. |
| Biochem/physiol Actions【生化/生理作用】 | Recombinant human PFKFB4 (2-end) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. PFKFB4 (also known as 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4) regulates the steady-state concentration of fructose-2, 6-bisphosphate, a potent activator of a key regulatory enzyme of glycolysis pathway called phosphofructokinase. Isozymes of PFKFB differ in the regions surrounding the catalytic core, which are important for the differential response to allosteric effectors and hormonal signals in different tissues (1). PFKFB4 is highly expressed in brain, heart, liver, muscle, placenta, adipose tissue, ovary, fallopian tubes, and testis (2). |
| Reconstitution【重悬】 | Formulated in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol. |
产品说明
| Storage and Stability【储存及稳定性】 | Store in aliquots at -70℃. Avoid freeze/thaw cycles. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
