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Saxagliptin hydrate
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4140487 | 10 MG | 968 | |||
| 4140487 | 50 MG | 3400 |
产品别名
945667-22-1
Saxagliptin hydrate
BMS477118-11
BMS-477118
(S)-3-Hydroxyadamantylglycine-L-cis-4,5-methanoprolinenitrile hydrate
BMS 477118
BMS-477118-11
BMS 477118-11
BMS477118
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H25N3O2 · H2O |
| Molecular weight | 333.43 |
| Biochem/physiol Actions【生化/生理作用】 | Saxagliptin (BMS-477118) is an orally active, highly potent and long-acting dipeptidyl peptidase IV inhibitor (human DPP-IV Ki = 0.9 nM; plasma DDP-IV inhibition = 87% 0.5-4h post 4 μmol/kg po. in normal rats) with therapeutic efficacy against type 2 diabetes in vivo (plasma glucose clearance = 28/43/61% post 0.3/1.0/3.0 μmol/kg po. in Zucker fa/fa rats). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC12CC([C@@H](C(N3[C@@H](C[C@]4([C@@]3(C4)[H])[H])C#N)=O)N)(CC(C5)C2)CC5C1.O |
