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SERPIN F1 human
| 产品编号： | 4140526 |
| 规格： | recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE) |
| 包装规格： | 10 μG，50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
SERPIN F1 human
Serpin F1
PEDF
PIG35
EPC-1
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Serpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions. |
| Physical form【外形】 | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
| Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in HEK 293 cells |
| tag【标签】 | 6-His tagged (C-terminus) |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | calculated mol wt 45.2 kDa observed mol wt 45-55 kDa (DTT-reduced. Protein migrates due to glycosylation. Gln 20 is the predicted N-terminal.) |
| packaging【包装】 | pkg of 10 μg pkg of 50 μg |
| UniProt accession no.【UniProt登记号】 | P36955 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SERPINF1(5176) |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
