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辛伐他汀

Simvastatin
产品编号:4140591
规格:British Pharmacopoeia (BP) Reference Standard
CAS NO:79902-63-9
包装规格:100 MG
产品类别:进口试剂
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4140591100 MG2080
产品别名

79902-63-9

辛伐他汀

Simvastatin

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C25H38O5
Molecular weight
418.57
MDL number
MFCD00072007
NACRES
NA.24
General description【一般描述】
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Biochem/physiol Actions【生化/生理作用】
辛伐他汀是HMG-CoA还原酶的特异性抑制剂,HMG-CoA还原酶是催化HMG-CoA转化为甲羟戊酸的酶,其是胆固醇生物合成的早期步骤。由于它可以降低低密度脂蛋白和甘油三酯的水平,并提高高密度脂蛋白水平,因而可用于治疗高胆固醇血症。辛伐他汀是一种内酯,其在体内 易于水解成相应的β-羟基酸,并可以在使用前用溶于EtOH中的NaOH进行活化。它是洛伐他汀的合成类似物(货M2147)。
Other Notes【其他说明】
Sales restrictions may apply.
产品性质
grade【等级】
pharmaceutical primary standard
manufacturer/tradename
BP
mp
127-132 ℃ (lit.)
format【格式】
neat
storage temp.【储存温度】
−20℃
SMILES string
[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)C(C)(C)CC
InChI
1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChI key
RYMZZMVNJRMUDD-HGQWONQESA-N
Gene Information
human ... HMGCR(3156)
packaging【包装】
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
安全信息
Pictograms【象形图】
GHS08
Signal word【警示用语:】
Warning
Hazard Statements
H361d
Precautionary Statements
P201 - P202 - P280 - P308 + P313 - P405 - P501
Hazard Classifications【危险分类】
Repr. 2
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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