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Thiol-dPEG®4-acid
产品别名
Thiol-dPEG®4-acid
HS-PEG4-COOH
Carboxy-PEG4-thiol
thiol-PEG-acid
Thiol-PEG4-acid
Thiol-PEG4-COOH
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H22O6S |
| Molecular weight | 282.35 |
| MDL number | MFCD11041132 |
| Features and Benefits【特点和优势】 | Thiol-dPEG4-acid is a sulfhydryl-containing, crosslinking PEGylation reagent that has a cross-bridge of monodisperse polyethylene glycol. The single molecular weight, discrete-length PEG (dPEG) chain is 16 atoms (18.3 Å) long. The sulfhydryl end of the crosslinker reacts with gold (forming dative bonds) and with thiol-reactive functional groups such as maleimide, bromoacetyl, SPDP, and thiol. The carboxylic acid end of the molecule couples to free amines using EDC or any suitable carbodiimide. An acylating agent such as N-hydroxysuccinimide (NHS) or 2,3,5,6-tetrafluorophenol (TFP) can enhance coupling efficiency. The carboxylate must react after the sulfhydryl conjugation. |
| Legal Information【法律信息】 | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 dPEG is a registered trademark of Quanta BioDesign |
产品性质
| Assay【测定】 | >95% (HPLC) |
| form【形式】 | solid or viscous liquid |
| reaction suitability | reaction type: Pegylations |
| polymer architecture【聚合物结构设计】 | shape: linear functionality: heterobifunctional |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
