您的位置：首页 > 产品中心 > 274693-27-5， 替格瑞洛
替格瑞洛
Ticagrelor
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4141013 | 10 MG | 854 | |||
| 4141013 | 50 MG | 1650 |
产品别名
274693-27-5
替格瑞洛
Ticagrelor
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylthio)-3H-[1,2,3]-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1 S ,2 S ,3 R ,5 S )-3-[7-{[(1 R ,2 S )-2-(3,4-二氟苯基)环丙基] 氨基 }-5-(丙基砜基)-3 H - [1,2,3] 三唑 [4,5- d 嘧啶-3-基]-5-(2-羟乙氧基)-1,2-环戊二醇
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H28F2N6O4S |
| Molecular weight | 522.57 |
| MDL number | MFCD09954148 |
| General description【一般描述】 | Ticagrelor (AZD6140) is a cyclopentyl-triazolopyrimidine. |
| Biochem/physiol Actions【生化/生理作用】 | Ticagrelor is an antithrombotic antiplatelet drug that acts by direct and reversible competitive inhibition of the adensoine purinoceptor P2Y12 receptor. It has clinical benefits in people affected with acute coronary syndrome. It might also play a beneficial role on endothelial function. Ticagrelor can prevent the uptake of adenosine by human erythrocytes and can promote the liberation of adenosine triphosphate (ATP) from human erythrocytes. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D -55 to -65°, c = 0.2 in methanol |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CCCSC1=NC(N[C@@]2([H])[C@@](C3=CC=C(F)C(F)=C3)([H])C2)=C4C(N([C@@]5([H])[C@H](O)[C@H](O)[C@@H](OCCO)C5)N=N4)=N1 |
| InChI | 1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1 |
| InChI key | OEKWJQXRCDYSHL-FNOIDJSQSA-N |
| Gene Information | human ... P2RY12(64805) |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
