您的位置：首页 > 产品中心 > 202796-42-7， UCB35625
UCB35625
产品别名
202796-42-7
UCB35625
trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethyl-piperidinium iodide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C30H37Cl2IN2O2 |
| Molecular weight | 655.44 |
| MDL number | MFCD09971133 |
| Biochem/physiol Actions【生化/生理作用】 | UCB35625 is a high affinity antagonist for CCR1 and CCR3 receptors. Also both UCB35625 and its enantiomer J113863 exhibit low binding affinity toward CCR2 and CCR5 where they activate three Gi and two G0 protein isoforms. UCB35625 does not activate G12 protein isoform. J113863 binding to CCR2 and CCR5 induce the recruitment of b-arrestin 2 whereas UCB35625 did not. J113863 and UCB35625 are biased ligands for the chemokine receptors CCR2 and CCR5. |
产品性质
| Assay【测定】 | >97% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
