VEGI/TNFSF-15 human

NA.32

VEGI (Vascular Endothelial Growth Inhibitor) is a member of the tumor necrosis factor family. VEGI is predominantly an endothelial cell-specific gene, and recombinant VEGI is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. VEGI exerts two activities of endothelial cells: early Gl arrest of G0/G1-cells responding to growth stimuli, and programmed cell death. VEGI is also able to regulate the expression of several important genes involved in angiogenesis. Human VEGF is a 21.8 kDa homodimeric protein consisting of 192 amino acid polypeptide chains.

Lyophilized from a solution containing 0.5 M NaCl, 50 mM Tris-HCl, pH 7.5.

Reconstitute in water to a concentration of 0.1–1.0 mg/mL. This solution can then be diluted into other aqueous buffers.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

human

expressed in E. coli

≥95% (HPLC)
≥95% (SDS-PAGE)

lyophilized

~21.8 kDa

pkg of 10 μg

avoid repeated freeze/thaw cycles

endotoxin, tested

AAR98573

O95150

wet ice

−20℃

human ... TNFSF15(41019336)