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VU041
产品别名
332943-64-3
VU041
VU0048041
1,2,3,4-Tetrahydro-1-[[4,5,6,7-tetrahydro-3-(trifluoromethyl)-1H-indazol-1-yl]acetyl]-quinoline
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)ethan-1-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H20F3N3O |
| Molecular weight | 363.38 |
| Biochem/physiol Actions【生化/生理作用】 | VU041 is a mosquito cuticle penetrant, potent and selective inhibitor of inwardly rectifying potassium (Kir) channel of Aedes aegypti (AeKir1) and Anopheles gambiae (AnKir1) that exhibits potent toxicity to adult insecticide-susceptible and -resistant strains of female mosquitoes. VU041 is selective for mosquito Kir channels over several mammalian orthologs. Also, VU041 is toxic to mosquito larvae when present in water. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(CN1N=C(C2=C1CCCC2)C(F)(F)F)N3CCCC4=C3C=CC=C4 |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
