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Zotarolimus
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4141600 | 5 MG | 1150 | |||
| 4141600 | 25 MG | 4240 |
产品别名
221877-54-9
Zotarolimus
ABT-578
(42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C52H79N5O12 |
| Molecular weight | 966.21 |
| MDL number | MFCD09752954 |
| Biochem/physiol Actions【生化/生理作用】 | Zotarolimus (ABT-578) is a semi-synthetic rapamycin analog with immunosuppressant and anti-proliferative activity. It binds to the FKBP12 binding protein, which subsequently binds to the mammalian target of rapamycin (mTOR) causing cell cycle arrest in the G1 phase. Zotarolimus was designed to be used for delivery from drug-eluting coronary stents to prevent restenosis. Zotarolimus is a second generation Drug Eluting Stent (DES). |
产品性质
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | C[C@H](CC[C@@H](C[C@H](OC)/C(C)=C/C=C/C=C/[C@H](C[C@H](C([C@H](OC)[C@@H](/C(C)=C/[C@@H](C)C1=O)O)=O)C)C)O2)[C@]2(O)C(C(N3CCCC[C@H]3C(O[C@H]([C@H](C)C[C@@H]4CC[C@H](N5N=NN=C5)[C@H](OC)C4)C1)=O)=O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
