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4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid
产品别名
1236196-77-2
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid
Probe building block
Carboxyl benzophenone alkyne
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H12O4 |
| Molecular weight | 280.27 |
| MDL number | MFCD21648478 |
| Application【应用】 | 4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. |
| Other Notes【其他说明】 | Technology Spotlight: Trifuctional Probe Building Blocks A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS Synthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3 Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | solid |
| reaction suitability | reaction type: click chemistry reagent type: cross-linking reagent |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(C(O)=O)C=C2 O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(C(O)=O)C=C2 |
| packaging【包装】 | 100 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
