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Adefovir Dipivoxil
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4143713 | 50 MG | 1190 | |||
| 4143713 | 100 MG | 2200 |
产品别名
142340-99-6
Adefovir Dipivoxil
9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H32N5O8P |
| Molecular weight | 501.47 |
| MDL number | MFCD00869897 |
| PubChem Substance ID【PubChem化学物质编号】 | 329771057 |
| Application【应用】 | Adefovir is used to treat hepatitis B infections. It is used to study organ-specific toxicity and immune mechanisms of Adefovir treatment. |
| Biochem/physiol Actions【生化/生理作用】 | Adefovir is an antiviral acyclic nucleoside phosphonate (ANP) analog that works by blocking reverse transcriptase. It is an inhibitor of duck hepatitis B virus (DHBV) replication that inhibits covalently closed circular DNA (CCC DNA) amplification. Cytotxicity is induced by Human Renal Organic Anion Transporter 1 (hOAT1). Adefovir is an Inhibitor of edema factor (EF)-induced cAMP accumulation and changes in cytokine production in mouse primary macrophages . |
| Other Notes【其他说明】 | Keep container tightly closed in a dry and well-ventilated place. |
产品性质
| biological source【生物来源】 | synthetic |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| solubility【溶解性】 | ethanol: 50 mg/mL |
| Mode of action【作用机制】 | enzyme | inhibits |
| antibiotic activity spectrum【抗生素抗菌谱】 | viruses |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC(C)(C)C(=O)OCOP(=O)(COCCn1cnc2c(N)ncnc12)OCOC(=O)C(C)(C)C |
| InChI | 1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23) |
| InChI key | WOZSCQDILHKSGG-UHFFFAOYSA-N |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 + H312 + H332 |
| Precautionary Statements | P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
