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CCW16
产品别名
2361138-33-0
CCW16
E3 ubiquitin ligase ligand
N-Benzyl-2-chloro-N-(4-(4-methoxyphenoxy)phenyl)acetamide
RNF4-targeting ligand
Ligand for PROTAC research
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H20ClNO3 |
| Molecular weight | 381.85 |
| Application【应用】 | CCW16 is targeting ligand for the E3 ubiquitin ligase RNF4 (RING finger protein 4) and can be used in targeted protein degradation (TPD) research or in the synthesis of protein degraders. Learn more about proteolysis-targeting chimeras (PROTAC degraders) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation. |
| Other Notes【其他说明】 | Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Portal: Building PROTAC® Degraders for Targeted Protein Degradation Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications Targeted Protein Degradation by Small Molecules Small-Molecule PROTACS: New Approaches to Protein Degradation Targeted Protein Degradation: from Chemical Biology to Drug Discovery |
| Legal Information【法律信息】 | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | powder |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1 COC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1 |
安全信息
| Pictograms【象形图】 | GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H410 |
| Precautionary Statements | P273 - P391 - P501 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
