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二钠盐-CAS 53005-05-3-Calbiochem
DIDS, Disodium Salt-CAS 53005-05-3-Calbiochem
| 产品编号： | 4144516 |
| 规格： | Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. |
| CAS NO： | 53005-05-3 |
| 包装规格： | 250 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
53005-05-3
二钠盐-CAS 53005-05-3-Calbiochem
DIDS, Disodium Salt-CAS 53005-05-3-Calbiochem
4,4'-Diisothiocyanostilbene-2,2'-disulfonic Acid, 2Na
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H8N2O6S4 · 2Na |
| Molecular weight | 498.48 |
| General description【一般描述】 | Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties. Binds covalently and irreversibly to the outer surface of human erythrocyte membrane proteins. Inhibits ATP transport into the endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl- uptake (IC50 = 150 nM) in neuroblastoma cells. Has antiulcerous activity. |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target Cl- uptake Target IC50: 150 nM inhibiting Cl- uptake in neuroblastoma cells Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Irritant (B) |
| Other Notes【其他说明】 | Bettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375. Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117. Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659. Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol.15, 207. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥85% (TLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated protect from light |
| color【颜色】 | yellow |
| solubility【溶解性】 | water: 0.5% |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C16H10N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h1-8H,(H,19,20,21)(H,22,23,24)/b2-1+ |
| InChI key | YSCNMFDFYJUPEF-OWOJBTEDSA-N |
| packaging【包装】 | 250 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
