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InSolution Caspase-8 Inhibitor II-Calbiochem
| 产品编号： | 4145190 |
| 规格： | The InSolution |
| 包装规格： | 250 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
InSolution Caspase-8 Inhibitor II-Calbiochem
Granzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
基本信息
| Empirical Formula【经验(实验)分子式】 | C30H43FN4O11 |
| Molecular weight | 654.68 |
| General description【一般描述】 | A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B. |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target caspase-8 Product does not compete with ATP. Cell permeable: yes Reversible: no |
| Warning【警告】 | Toxicity: Irritant (B) |
| Sequence【序列】 | Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F* |
| Physical form【外形】 | A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. |
| Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-20°C). |
| Analysis Note【分析说明】 | single spot by TLC |
| Other Notes【其他说明】 | Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345. Sweeney, E.A., et al. 1998. FEBS Lett.425, 61. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 250 μg in Glass bottle Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
| Flash Point(F)【闪点(F)】 | 188.6 °F - (refers to pure substance) |
| Flash Point(C)【闪点(C)】 | 87 ℃ - (refers to pure substance) |
