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N-(But-3-yn-1-yl)-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)acrylamide
产品别名
N-(But-3-yn-1-yl)-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)acrylamide
Coumarin alkyne CoLDR probe
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H15NO4 |
| Molecular weight | 297.31 |
| Application【应用】 | N-(But-3-yn-1-yl)-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)acrylamide is a proteomic cysteine probe. As described in Reddi et al, the Nir London lab developed a-substituted N-alkynyl-methacrylamides for covalent ligand directed release chemistry (CoLDR). CoLDR represents a new type of acrylamide-based electrophiles for targeted covalent inhibitor discovery and design. Specifically this CoLDR probe is a coumarin derivative with a terminal alkyne for click chemistry. |
| Other Notes【其他说明】 | Chemical Biology Tools Click Chemistry Reagents |
产品性质
| reaction suitability | reagent type: chemical modification reagent reaction type: click chemistry |
| Quality Level【质量水平】 | 100 |
| functional group【官能团】 | (Alkyne) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C1OC2=CC(OCC(C(NCCC#C)=O)=C)=CC=C2C=C1 |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
