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Nebivolol Hydrochloride

产品编号:4145812
规格:United States Pharmacopeia (USP) Reference Standard
CAS NO:152520-56-4
包装规格:150 MG
产品类别:进口试剂
品牌:USP
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4145812150 MG19140
产品别名

152520-56-4

Nebivolol Hydrochloride

R-65824

rel-(aR,a′R,2R,2′S)-a,a′-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] hydrochloride

Narbivolol

Nebilet

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C22H25F2NO4 · HCl
Molecular weight
441.90
NACRES
NA.24
General description【一般描述】
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Biochem/physiol Actions【生化/生理作用】
Nebivolol is a competitive, highly selective b1-receptor antagonist with mild vasodialating properties, possibly due to an interaction with the L-arginine/ NO pathway, and is used for treatment of essential hypertension. It is 40-fold selective for β1 vs. β2, and lacks ISA (intrinsic sympathomimetic activity).
Analysis Note【分析说明】
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Other Notes【其他说明】
USP issued SDS can be found here.
Sales restrictions may apply.
产品性质
grade【等级】
pharmaceutical primary standard
manufacturer/tradename
USP
format【格式】
neat
storage temp.【储存温度】
2-8℃
SMILES string
Cl.O[C@@H](CNC[C@H](O)[C@@H]1CCc2cc(F)ccc2O1)[C@H]3CCc4cc(F)ccc4O3
InChI
1S/C22H25F2NO4.ClH/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22;/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2;1H/t17-,18-,21-,22+;/m0./s1
InChI key
JWEXHQAEWHKGCW-BIISKSHESA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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