Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)

HO[CH(CH₃)COO]_m[CH₂CH₂O]_nCH₃

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide) is an amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics).

100

solid

PDLA average M_n 50,000 (by NMR)
PDLA average M_n 50000
PEG average M_n 5,000 (by NMR)
PEG average M_n 5000

white to yellow

2-8℃

11 - Combustible Solids

WGK 3