丙酰-L-肉碱

C₁₀H₁₉NO₄

217.26

MFCD00870024

NB.21

Propionyl-L-carnitine (PLC), a natural odd-carbon-number, endogenous ester of L-carnitine, is found to be present in humans and animals as a minor component compared to L-carnitine (LC) and acetyl-L-carnitine (ALC). It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

Propionyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography-based techniques. It may also be used as an analytical standard in monitoring the analyte in chemical synthesis procedures and pharmaceutical formulations using a stereospecific enzyme assay and high-performance liquid chromatography technique with UV detection.

analytical standard

100

≥94.0% (HPLC)

[α]/D -24.0±2.0°, c = 0.2 in H₂O

limited shelf life, expiry date on the label

≤13% water ((calculated from elemental analysis)

clinical testing

neat

2-8℃

[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O

1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1

UFAHZIUFPNSHSL-MRVPVSSYSA-N

11 - Combustible Solids

WGK 3